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KMID : 1189420200330030115
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2020 Volume.33 No. 3 p.115 ~ p.124
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Review about using Herbal medicine on steroid tapering and steroid overuse in Skin disease
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Han Chang-Yi
Kim Jun-Dong
Kang Dong-Won
Kim Kyu-Seok
Kim Yoon-Bum
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Abstract
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Objectives : The purpose of this study is to investigate the effect and side effects of steroids on dermatitis and skin barrier through lipid metabolism. And to propose using Herbal medicine to suppress Steroid rebound and prevent side effects.
Methods : We reviewed recent studies about the relationship between dermatitis, skin lipid, steroid, and herbal medicine through Google scholar.
Results : In various inflammatory skin diseases, the corticosteroid is selected as the primary drug due to its strong anti-inflammatory and immunosuppressive effect. However, long-term use of steroids has a variety of side effects, especially lipid metabolism disruption, which aggravates skin barrier damage underlying various skin diseases and is more susceptible to inflammatory reactions.
Conclusions : Herbal medicine is used as a comprehensive approach, and it can be used to reduce the frequency of steroid exposure by protecting against barrier damage by controlling anti-inflammatory, antioxidant, and systemic/sebaceous lipid metabolism and stratum corneum protein differentiation.
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KEYWORD
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Dermatitis, Steroid, Side effect, Lipid barrier, Herbal medicine
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